Author

Katherine Ilia

Massachusetts Institute of TechnologyORCID 0000-0002-7205-5364Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Synthetic Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2

Frequent Co-Authors

Domitilla Del VecchioiD· 2 shared Ron WeissiD· 2 shared Ross D. JonesiD· 2 shared Benjamin X. WangiD· 1 shared Eliezer Aravera· 1 shared James J. CollinsiD· 1 shared Michael M. KaminskiiD· 1 shared Michael T. LaubiD· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersSynthetic Biology

Domitilla Del VecchioORCID

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2 papers

Recent·Most cited

Synthetic genetic circuits to uncover and enforce the OCT4 trajectories of successful reprogramming of human fibroblasts

Katherine Ilia, Nika Shakiba, Trevor Bingham, Ross D. Jones, Michael M. Kaminski, Eliezer Aravera, Simone Bruno, Sebastian Palacios, Ron Weiss, James J. Collins, Domitilla Del Vecchio, Thorsten M. Schlaeger

The paper identifies OCT4 trajectories critical for reprogramming human fibroblasts to iPSCs and develops a synthetic genetic circuit to enforce these trajectories, improving reprogramming efficiency.

Science Advances · Nov 29, 2023Peer-reviewedSynthetic Biology

Robust and tunable signal processing in mammalian cells via engineered covalent modification cycles

Ross D. Jones, Yili Qian, Katherine Ilia, Benjamin X. Wang, Michael T. Laub, Domitilla Del Vecchio, Ron Weiss

This paper develops synthetic phosphorylation-based signaling networks in mammalian cells that are tunable, precise, and robust to perturbations.

Nature Communications · Mar 31, 2022Peer-reviewedSynthetic Biology