Julian Varghese

This study identifies CD36 as a metabolic checkpoint sustaining Th2 cell tissue residency in allergic asthma by regulating GATA3 and PPARγ expression and interactions with dendritic cells.

This study identifies genome-wide DNA methylation changes during human spermatogenesis and their disruption in disturbed spermatogenesis, highlighting hypomethylation at specific regions and transposable elements.

The paper analyzes microvascular immune cells in mouse organs and compares them to peripheral blood, finding organ-specific immune responses that are not detectable in blood or tissue samples.

PuMA extracts and visualizes gene-celltype relations from PubMed to aid in celltype annotation.

This paper develops a data-driven method for analyzing fMRI data across studies, revealing consistent patterns in BOLD time series and demonstrating its generalizability and robustness.

The paper evaluates clinical checklists for genetic testing in pediatric oncology, finding low specificity and missing 25% of children with cancer predisposition variants.