Harriet de Wit

This study examines how a single dose of methamphetamine affects brain functional connectivity related to sustained attention and arousal in healthy adults.

This study identifies 14 genome-wide significant loci for delay discounting in 134,935 individuals and shows genetic associations with 212 medical conditions.

This study examines how methamphetamine affects learning rate dynamics in probabilistic reversal learning, showing it enhances learning flexibility more in individuals with lower baseline performance.

This study reanalyzes episodic memory data from 10 datasets to show how different drug classes uniquely affect recollection, familiarity, and metamemory during encoding, consolidation, and retrieval.

This study conducts GWAS on impulsive personality traits and drug experimentation in 22,861 adults, identifying genetic associations and correlations with psychiatric disorders.

GWAS in over one million individuals identify 611 loci across risk tolerance and risky behaviors, revealing shared genetic architecture and implicating glutamatergic and GABAergic neurotransmission.

The paper uses PCA to identify three latent components of risk-taking behavior from self-reports and behavioral tasks in young adults.

This study identifies 4 new risk loci for cannabis use through GWAS, finds genetic overlap with mental health, and shows a causal link between schizophrenia and cannabis use.

This study investigates conditioned nausea in humans using a controlled environment and emetic drug pairing, finding limited evidence of conditioned place aversion but a small increase in nausea in the drug-paired room.

This study identifies a genetic variant associated with delay discounting in European ancestry adults and links it to multiple traits and disorders.

This study conducts a GWAS on AUDIT scores in 20,328 European ancestry participants, finding no genome-wide significant loci but suggesting genetic correlations with AUD, alcohol consumption, and other traits.