Author

Pietro Biroli

University of ZurichORCID 0000-0002-5033-4688Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 7 Approach:statistical model· 7 Research Focus:GWAS / association mapping· 5 Assay:GWAS summary statistics· 5 Research Focus:polygenic risk· 3 Approach:benchmark study· 1 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1

Frequent Co-Authors

Elliot M. Tucker–DrobiD· 4 shared K. Paige HardeniD· 4 shared Abdel AbdellaouiiD· 3 shared Aysu OkbayiD· 3 shared Margherita MalanchiniiD· 3 shared Michel Guillaume NivardiD· 3 shared Philipp KoellingeriD· 3 shared Andrew David GrotzingeriD· 2 shared

Activity by Year

2018-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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4 shared papersGenetics

Elliot M. Tucker–DrobORCID

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Author profile →

8 papers

Recent·Most cited

Genomics of Educational Attainment Across 80 Years of Social and Political Transformation in Germany

Deniz Fraemke, Anna Miller, Philipp Koellinger, Ralph Hertwig, David Richter, Sabine Zinn, Christian Kandler, Andreas J. Forstner, Bastian Mönkediek, Martin Diewald, Alexander Teumer, Sebastian Edgar Baumeister, Henry Völzke, Uwe Völker, Hans Jörgen Grabe, , Laurel Raffington

The paper examines how polygenic indices for educational attainment change across birth cohorts and regions in Germany, finding stronger associations in recent cohorts and the East but weaker effects for women.

bioRxiv · Sep 21, 2026 · PreprintGenomics

Cohort Profile: Genetic data in the German Socio-Economic Panel Innovation Sample (Gene-SOEP)

Philipp Koellinger, Aysu Okbay, Hyeokmoon Kweon, Annemarie Schweinert, Richard Karlsson Linnér, Jan Goebel, David Richter, Lisa Reiber, Bettina Maria Zweck, Daniel W. Belsky, Pietro Biroli, Rui Mata, Elliot M. Tucker–Drob, K. Paige Harden, Gert G. Wagner, Ralph Hertwig

The paper describes the Gene-SOEP dataset, a longitudinal genetic study of 2,598 individuals in Germany, providing polygenic indices for research on genetic-environment interactions.

PLoS ONE · Nov 29, 2023Peer-reviewedGenetics

Genetic contributions of noncognitive skills to academic development

Margherita Malanchini, Andrea G. Allegrini, Michel Guillaume Nivard, Pietro Biroli, Kaili Rimfeld, Rosa Cheesman, Sophie von Stumm, Perline Demange, Elsje van Bergen, Andrew David Grotzinger, Laurel Raffington, Javier de la Fuente, Jean‐Baptiste Pingault, K. Paige Harden, Elliot M. Tucker–Drob, Robert J. Plomin

This study shows noncognitive skills become more predictive of academic achievement over time and their genetic contribution increases with age.

bioRxiv · Apr 3, 2023 · PreprintGenetics

Overcoming Attenuation Bias in Regressions using Polygenic Indices: A Comparison of Approaches

Hans van Kippersluis, Pietro Biroli, Rita Dias Pereira, T. J. Galama, Stephanie von Hinke, S. Fleur W. Meddens, Dilnoza Muslimova, Eric A.W. Slob, Ronald de Vlaming, Cornelius A. Rietveld

This paper compares two methods to reduce measurement error in polygenic indices by simulating and validating their performance on educational attainment and height data.

bioRxiv · Apr 9, 2021 · PreprintGenetics

Moral Hazard Heterogeneity: Genes and Insurance Influence Smoking after a Health Shock

Pietro Biroli, Laura Zwyssig

The paper examines how genetic predisposition and insurance status interact to influence smoking behavior after a health shock, finding that genetic factors affect the response to insurance coverage.

bioRxiv · Mar 5, 2021 · PreprintGenetics

Investigating the Genetic Architecture of Non-Cognitive Skills Using GWAS-by-Subtraction

Perline Demange, Margherita Malanchini, Travis T. Mallard, Pietro Biroli, Simon R. Cox, Andrew David Grotzinger, Elliot M. Tucker–Drob, Abdel Abdellaoui, Louise Arseneault, Elsje van Bergen, Dorret Irene Boomsma, Avshalom Caspi, David L. Corcoran, Benjamin W. Domingue, Kathleen Mullan Harris, , Michel Guillaume Nivard

This study identifies 157 genome-wide significant loci associated with non-cognitive contributions to educational attainment, explaining 57% of genetic variance.

Nature Genetics · Jan 1, 2021Peer-reviewedGenetics

Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences

Richard Karlsson Linnér, Pietro Biroli, Edward L. Kong, S. Fleur W. Meddens, Robbee Wedow, Mark Alan Fontana, Maël P. Lebreton, Abdel Abdellaoui, Anke R. Hammerschlag, Michel Guillaume Nivard, Aysu Okbay, Cornelius A. Rietveld, Pascal N. Timshel, Stephen P. Tino, Maciej Trzaskowski, , Jonathan P. Beauchamp

GWAS in over one million individuals identify 611 loci across risk tolerance and risky behaviors, revealing shared genetic architecture and implicating glutamatergic and GABAergic neurotransmission.

bioRxiv · Jan 8, 2019 · PreprintGenetics

Childhood socioeconomic status moderates genetic predisposition for peak smoking

Laura Jean Bierut, Pietro Biroli, T. J. Galama, Kevin Thom

The paper examines how childhood socioeconomic status interacts with genetic risk to influence peak cigarette consumption in adulthood.

bioRxiv · Jun 3, 2018 · PreprintGenomics