Oncolytic Reovirus mediates innate-driven SARS-CoV-2 elimination in the absence of cell toxicity
Samantha Yolotzin García Cárdenas, Gemma Swinscoe, Amy Moran, Liam Barningham, Graham P. Cook, Adel Samson, Sam J. Wilson, Michael H. Malim, Russell Hughes, Stephen D. C. Griffin
This paper shows that oncolytic Reovirus can eliminate SARS-CoV-2 in lung cells without causing toxicity by enhancing innate antiviral responses.
bioRxiv · Dec 18, 2025 · PreprintImmunology