Combined quantification of intracellular (phospho-)proteins and transcriptomics from fixed single cells.
Jan P. Gerlach, Jessie A.G.L. van Buggenum, Sabine E.J. Tanis, Mark Hogeweg, Branco M. H. Heuts, Mauro J. Muraro, Lisa Elze, Francesca Rivello, Agata Rakszewska, Alexander van Oudenaarden, Wilhelm T. S. Huck, Hendrik G. Stunnenberg, Klaas W. Mulder
The paper introduces RAID, a method to analyze both transcriptomes and intracellular phosphoproteins from fixed single cells, showing its ability to detect heterogeneity in cellular responses.
Scientific Reports · Feb 6, 2019Peer-reviewedGenomics