Author

Cole Dolamore

University of Nebraska–LincolnORCID 0000-0002-7274-1014Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Approach:statistical model· 1

Frequent Co-Authors

Doeke R. HekstraiD· 2 shared Kara A. ZielinskiiD· 2 shared Kevin M. DaltoniD· 2 shared Lois PollackiD· 2 shared Mark A. WilsoniD· 2 shared Robert William HenningiD· 2 shared V. ŠrajeriD· 2 shared Harrison K. WangiD· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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2 shared papersBiophysics

Doeke R. HekstraORCID

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2 papers

Recent·Most cited

Scaling and Merging Time-Resolved Laue Data with Variational Inference

Kara A. Zielinski, Cole Dolamore, Harrison K. Wang, Robert William Henning, Mark A. Wilson, Lois Pollack, V. Šrajer, Doeke R. Hekstra, Kevin M. Dalton

This paper applies variational inference to time-resolved diffraction data of an enzyme to extract high signal-to-noise changes in electron density and evaluates hyperparameter impact.

Structural Dynamics · Nov 1, 2024Peer-reviewedBiophysics

Resolving DJ-1 Glyoxalase Catalysis Using Mix-and-Inject Serial Crystallography at a Synchrotron

Kara A. Zielinski, Cole Dolamore, Kevin M. Dalton, Nathan Smith, John S. Termini, Robert William Henning, V. Šrajer, Doeke R. Hekstra, Lois Pollack, Mark A. Wilson

This study uses mix-and-inject serial crystallography to resolve the catalytic mechanism of DJ-1, showing it catalyzes nearly two turnovers and reveals allosteric communication during glyoxalase activity.

bioRxiv · Jul 19, 2024 · PreprintBiochemistry