Mark A. Wilson

This study determines two distinct structures of soybean lipoxygenase-1 from a single experiment, showing that conformational flexibility is influenced by crystal solvent content.

This paper investigates suicide Thi4 thiazole synthases, showing genomic evidence suggesting non-suicidal function and supporting this with functional experiments in E. coli.

This study uses neutron crystallography and simulations to analyze proton sharing in low-barrier hydrogen bonds in DJ-1 and YajL, showing how mutations affect proton delocalization and mobility.

This paper demonstrates how mass spectrometry-based proteomics can be used in continuous directed evolution to analyze protein modifications and network integration during evolution.

This paper applies variational inference to time-resolved diffraction data of an enzyme to extract high signal-to-noise changes in electron density and evaluates hyperparameter impact.

This study uses mix-and-inject serial crystallography to resolve the catalytic mechanism of DJ-1, showing it catalyzes nearly two turnovers and reveals allosteric communication during glyoxalase activity.