Novel GC-MS/MS Strategy for Fructose Quantification and Stable Isotope Tracing: Development, Validation, and SIM vs MRM Comparison
Melany Ríos-Morales, Florine H.M. Westerbeke, Max Nieuwdorp, Frédéric Maxime Vaz, Dewi van Harskamp
This paper develops and validates a GC-QQQ method for measuring unlabeled and 13C6-fructose in human plasma, showing improved sensitivity and lower LLOQs compared to SIM.
bioRxiv · Aug 25, 2026 · PreprintBiochemistry