Cell BiologybioRxiv
Targeting IRE1alpha improves insulin sensitivity and thermogenesis and suppresses metabolically active adipose tissue macrophages in male obese mice
Dan Wu, Venkateswararao Eeda, Zahra Maria…·Weidong Wang
This study shows that inhibiting IRE1 improves insulin sensitivity, thermogenesis, and reduces metabolically active adipose tissue macrophages in obese mice.
6 citations