Author

Gaochen Jin

Department of Chemical and Biomolecular Engineering, University of Pennsylvania, Philadelphia, Pennsylvania, USA;ORCID 0000-0002-7279-3623Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:scRNA-seq· 2 Research Focus:trajectory inference· 2 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Bomyi LimiD· 2 shared Chin Nien LeeiD· 1 shared Daniel Oh· 1 shared David E. Reynolds· 1 shared Emilia A. Leyes PorelloiD· 1 shared Emily HuynhiD· 1 shared Jianhua Lim· 1 shared Jina KoiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersBioengineering

Bomyi LimORCID

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2 papers

Recent·Most cited

BioengineeringbioRxivPreprintNov 4, 2026

Live Droplet Single-Cell RNA Sequencing

David E. Reynolds, Sangmo Lee, Daniel Oh…·Jina Ko

The paper introduces Live D-seq, a method for longitudinal, non-destructive single-cell RNA sequencing, and demonstrates its ability to track cellular dynamics over time.

DOI 10.64898/2026.11.03.763484

humanscRNA-seq

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Molecular BiologybioRxivPreprintMar 17, 2025

Heterogeneous Sox2 transcriptional dynamics mediate pluripotency maintenance in mESCs in response to LIF signaling perturbations

Gaochen Jin, Emilia A. Leyes Porello, Jingchao Zhang, Bomyi Lim

This study investigates how LIF signaling perturbations affect Sox2 transcriptional dynamics in mESCs, revealing that reduced Sox2 expression, not complete loss, drives pluripotency loss.

1 citation

mousescRNA-seq

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