Author

Jo Wrigglesworth

Deakin UniversityORCID 0000-0002-9251-4775Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:DNA methylation· 3 Organism:human· 3 Approach:statistical model· 3 Research Focus:differential expression· 2 Approach:benchmark study· 1 Research Focus:benchmarking· 1 Assay:imaging· 1

Frequent Co-Authors

Valentine ChirokoffiD· 3 shared Peter FransquetiD· 2 shared Timothy J. SilkiD· 2 shared Ai Ling Teh· 1 shared Ai Peng TaniD· 1 shared Amalia M. SkybergiD· 1 shared Anke Huels· 1 shared Catherine J. WedderburniD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersGenomics

Valentine ChirokoffORCID

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3 papers

Recent·Most cited

Genetic and environmental factors associated with DNA methylation across childhood and adolescence in individuals with and without attention-deficit/hyperactivity disorder

Jo Wrigglesworth, Valentine Chirokoff, Peter Fransquet, Vicki A. Anderson, Mark A. Bellgrove, Timothy J. Silk

The paper identifies genetic and environmental factors influencing DNA methylation in ADHD and controls across childhood, showing income and school quality affect methylation changes differently by ADHD trajectory.

bioRxiv · Oct 22, 2026 · PreprintGenomics

Epigenetic and brain age across development: Performance and associations in the MIND consortium

Marlene Staginnus, Vilte Baltramonaityte, Isabel K. Schuurmans, Sarina Abrishamcar, Martin Bauer, Sintia Iole Belangero, Elisabeth B. Binder, Rodrigo A. Bressan, Sybil Alexandra Burt, Claudia Buß, Shi Yu Chan, Valentine Chirokoff, Shaunna Clark, H. Valerie Curran, Darina Czamara, , Esther Walton

Across 15 cohorts (birth to 24 years), 20 epigenetic clocks and eight brain age models predicted chronological age modestly, stabilizing by middle childhood; their age residuals were weakly associated.

bioRxiv · Jul 30, 2026 · PreprintNeuroscience✦ In-depth digest

Longitudinal DNA methylation dynamics distinguish Persistent and Remitted ADHD in childhood and adolescence

Jo Wrigglesworth, Valentine Chirokoff, Peter D. Fransquet, Jeffrey M. Craig, Tim J. Silk

The paper examines DNA methylation changes in children and adolescents with ADHD, finding distinct patterns between remitted and persistent ADHD outcomes.

bioRxiv · Oct 21, 2025 · PreprintGenomics