Author

Ellen Paatela

University of MinnesotaORCID 0000-0002-7291-0850Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Developmental Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1 Approach:statistical model· 1

Frequent Co-Authors

Atsushi AsakuraiD· 1 shared Britney LeeiD· 1 shared Ce YuaniD· 1 shared Dane MunsoniD· 1 shared Daniel L. HoutziD· 1 shared Danielle C. HammiD· 1 shared Faith G St. Amant· 1 shared Jasmeet BhatiaiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperDevelopmental Biology

Atsushi AsakuraORCID

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2 papers

Recent·Most cited

A discrete region of the D4Z4 is sufficient to initiate epigenetic silencing

Ellen Paatela, Faith G St. Amant, Danielle C. Hamm, Sean R. Bennett, Taranjit S. Gujral, Silvère M. van der Maarel, Stephen J. Tapscott

The paper identifies a specific D4Z4 sequence that can epigenetically silence a reporter gene, revealing key regulators and mechanisms of DUX4 repression in skeletal muscle.

Human Molecular Genetics · Jun 27, 2025Peer-reviewedMolecular Biology

Per1/Per2-Igf2 axis-mediated circadian regulation of myogenic differentiation

Nobuko Katoku-Kikyo, Ellen Paatela, Daniel L. Houtz, Britney Lee, Dane Munson, Xuerui Wang, Mohammed Hussein, Jasmeet Bhatia, Seunghyun Lim, Ce Yuan, Yoko Asakura, Atsushi Asakura, Nobuaki Kikyo

This study shows that Per1 and Per2 regulate myoblast differentiation and muscle regeneration through Igf2 activation, creating a circadian time window for these processes.

The Journal of Cell Biology · Apr 27, 2021Peer-reviewedDevelopmental Biology