Yoko Asakura

This study investigates JAG2-related muscular dystrophy by examining the role of Notch signaling in muscle stem cells, finding that JAG2 variants disrupt both autocrine and paracrine Notch signaling, impairing muscle regeneration.

The paper identifies the VEGFA-FLT1-AKT1 pathway as promoting muscle stem cell survival through endothelial gene expression.

This study shows that Per1 and Per2 regulate myoblast differentiation and muscle regeneration through Igf2 activation, creating a circadian time window for these processes.

This study shows that inhibiting Flt1 improves the muscular dystrophy phenotype in mdx mice by increasing vascular density and reducing muscle pathology.