Author

Matteo Moretti

Ente Ospedaliero CantonaleORCID 0000-0002-7301-1208Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Research Focus:drug response / drug discovery· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:organoid / primary culture· 1

Frequent Co-Authors

Alberto Jesus. ArribasiD· 3 shared Alex ZadroiD· 3 shared Eleonora CannasiD· 3 shared Francesco BertoniiD· 3 shared Luciano CascioneiD· 3 shared Andrea RinaldiiD· 2 shared Filippo SprianoiD· 2 shared Giulio SartoriiD· 2 shared

Activity by Year

2025-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 42 mutual co-author links

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3 shared papersCancer Biology

Alberto Jesus. ArribasORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Targeting Aberrant FGFR Signaling with Infigratinib Enhances the Efficacy of BTK/PI3K Inhibitors and Bendamustine in Lymphoma Cells

Giulio Sartori, Alessandro Ghiringhelli, Eleonora Cannas, Francesca Guidetti, Alberto Jesus. Arribas, Alex Zadro, Luciano Cascione, Chiara Falzarano, Martina Imbimbo, Matteo Moretti, Andrea Rinaldi, Emanuela Lovati, Francesco Bertoni

This study shows that combining infigratinib with BTK/PI3K inhibitors or bendamustine improves efficacy in lymphoma cell models, reversing resistance and suggesting FGFR inhibition as a therapeutic strategy.

bioRxiv · Dec 25, 2025 · PreprintCancer Biology

High-Throughput Screening Identifies PLK1 Inhibition as a Strategy to Potentiate BTK Blockade in Marginal Zone Lymphoma

Alex Zadro, Alberto J. Arribas, Michela Robusto, Stefania Vultaggio, Adrian Andronache, Giovanni Fagà, Kristýna Kupcová, Eleonora Cannas, Filippo Spriano, Giulio Sartori, Luciano Cascione, Chiara Tarantelli, Sara Napoli, Andrea Rinaldi, Davide Rossi, , Francesco Bertoni

This study identifies PLK1 inhibition as a strategy to enhance BTK blockade in MZL by overcoming resistance through transcriptomic and mechanistic analysis.

bioRxiv · Oct 25, 2025 · PreprintCancer Biology

A High-Throughput Bone Marrow 3D Co-Culture System to Develop Resistance to B Cell Receptor Signaling Targeted Agents in B Cell Non-Hodgkin Lymphoma

Alex Zadro, Alberto J. Arribas, Maria Vittoria Colombo, Eleonora Cannas, Filippo Spriano, Luciano Cascione, Afua A. Mensah, Federico Simonetta, Dalila Petta, Chiara Arrigoni, Christian Candrian, Matteo Moretti, Francesco Bertoni

This paper develops a 3D co-culture system using bone marrow stromal cells to study drug resistance in B cell non-Hodgkin lymphoma and identifies potential resistance mediators.

bioRxiv · Jan 14, 2025 · PreprintCancer Biology