NeurosciencebioRxivPreprint
The neurovascular coupling response of the aged brain is brain-state dependent.
Xiao Zhang, Lechan Tao, Amalie Holm Nygaard…·Changsi Cai
This study shows that neurovascular coupling in aged mice is slower and prolonged, with reduced Ca2+ signaling in vascular mural cells, and correlates with decreased spontaneous locomotion.