Author

Lu Lu

New York Genome CenterORCID 0000-0002-7343-7161Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Lu Lu14 papers · University of Tennessee Health Science Center

Biology Disciplines

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Genomics· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:scRNA-seq· 2 Assay:CRISPR screen· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Organism:mouse· 1 Research Focus:perturbation response prediction· 1

Frequent Co-Authors

Neville E. SanjanaiD· 3 shared Eleni P. MimitouiD· 2 shared John A. MorrisiD· 2 shared Peter SmibertiD· 2 shared Zharko DaniloskiiD· 2 shared Akash Sookdeo· 1 shared Alejandro Méndez‐MancillaiD· 1 shared Anne Bruun RovsingiD· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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3 shared papersGenomics

Neville E. SanjanaORCID

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3 papers

Recent·Most cited

BioengineeringbioRxivPreprintFeb 20, 2026

Rational design of synthetic proteins using a genome-scale CRISPR screen

Wells H. Burrell, Simon J. Mueller, Zharko Daniloski…·Neville E. Sanjana

The paper designs synthetic proteins for precise gene editing using CRISPR screens and shows improved editing efficiency in various cell types.

1 citation

humanproteomics

GenomicsSciencePeer-reviewedMay 4, 2023

Discovery of target genes and pathways of blood trait loci using pooled CRISPR screens and single cell RNA sequencing

John A. Morris, Christina M. Caragine, Zharko Daniloski…·Neville E. Sanjana

The paper identifies target genes and pathways of blood trait loci using CRISPR screens and single-cell RNA sequencing, revealing cis and trans regulatory effects of noncoding variants.

208 citationstop 1%

humanCRISPR screen

GenomicsNature MethodsPeer-reviewedDec 22, 2022

Efficient combinatorial targeting of RNA transcripts in single cells with Cas13 RNA Perturb-seq

Hans‐Hermann Wessels, Alejandro Méndez‐Mancilla, Yuhan Hao…·Rahul Satija

The paper introduces CaRPool-seq, a method using Cas13 for combinatorial RNA perturbations in single cells, and applies it to study myeloid differentiation regulators in AML.

79 citationstop 2%