Systems BiologyNaturePeer-reviewed
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A global atlas of substrate specificities for the human serine/threonine kinome
Jared Lee Johnson, Tomer M. Yaron, Emily M. Huntsman…·Lewis C. Cantley
Positional scanning peptide arrays profile substrate sequence specificities across 303 human serine/threonine kinases, enabling computational kinase-substrate annotation and signaling pathway inference across the human phosphoproteome.