Alexandre Maucuer

This study identifies UHMK1 as a splicing regulatory kinase by showing its role in phosphorylation, alternative splicing, and cellular processes through integrated phosphoproteomics and RNA-seq analyses.

Positional scanning peptide arrays profile substrate sequence specificities across 303 human serine/threonine kinases, enabling computational kinase-substrate annotation and signaling pathway inference across the human phosphoproteome.