Author

Leslie Brian Essel

University of Missouri–Kansas CityORCID 0000-0002-7355-2530Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Ashis SinhaiD· 1 shared Ashley Edge· 1 shared Gabrielle A. Nickerson· 1 shared Matthew Y. Otsuka· 1 shared Russell T. MatthewsiD· 1 shared Samuel BouyainiD· 1 shared Seth M. Mejia· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperBiochemistry

Ashis SinhaORCID

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1 paper

Recent·Most cited

The hyaluronan-binding activity of aggrecan is important, but not essential, for its specific insertion into perineuronal nets

Matthew Y. Otsuka, Leslie Brian Essel, Ashis Sinha, Gabrielle A. Nickerson, Seth M. Mejia, Ashley Edge, Russell T. Matthews, Samuel Bouyain

This study reports the co-crystal structure of aggrecan's G1 region with and without HA and shows that HA-binding is important but not essential for its integration into perineuronal nets.

Journal of Biological Chemistry · Apr 22, 2025Peer-reviewedBiochemistry