Author

Russell T. Matthews

SUNY Upstate Medical UniversityORCID 0000-0002-9376-4215Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Assay:electronic health records· 1 Organism:mouse· 1 Research Focus:protein structure prediction· 1 Assay:proteomics· 1

Frequent Co-Authors

Ashis SinhaiD· 3 shared Gabrielle A. Nickerson· 2 shared Samuel BouyainiD· 2 shared Angelica M. KowalchukiD· 1 shared Ashley Edge· 1 shared Jessica L. MacDonaldiD· 1 shared Leslie Brian EsseliD· 1 shared Matthew Y. Otsuka· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersNeuroscience

Ashis SinhaORCID

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3 papers

Recent·Most cited

NeuroscienceJournal of NeurochemistryPeer-reviewedJun 1, 2026

Astrocytic Regulation of aberrant perineuronal net formation in Mecp2-null Neocortex

Ashis Sinha, Angelica M. Kowalchuk, Nasim Khatibi…·Jessica L. MacDonald

This study identifies Mecp2-null astrocytes as drivers of precocious perineuronal net formation in RTT by inducing Hapln1 expression and accelerating PNN maturation.

2 citations

mouseproteomics

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BiochemistryJournal of Biological ChemistryPeer-reviewedApr 22, 2025

The hyaluronan-binding activity of aggrecan is important, but not essential, for its specific insertion into perineuronal nets

Matthew Y. Otsuka, Leslie Brian Essel, Ashis Sinha…·Samuel Bouyain

This study reports the co-crystal structure of aggrecan's G1 region with and without HA and shows that HA-binding is important but not essential for its integration into perineuronal nets.

8 citations

experimental assayprotein structure prediction

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NeuroscienceJournal of Biological ChemistryPeer-reviewedApr 10, 2025

Contactin-1 is a critical neuronal cell surface receptor for perineuronal net structure

Ashis Sinha, Gabrielle A. Nickerson, Samuel Bouyain, Russell T. Matthews

5 citations

experimental assay

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