Samuel Bouyain

This study reports the co-crystal structure of aggrecan's G1 region with and without HA and shows that HA-binding is important but not essential for its integration into perineuronal nets.

The paper evaluates crystal diffraction data quality metrics, finding that low-shell values of Rmerg, Rmeas, Rpim, and CC1/2 indicate Laue symmetry correctness, while high-shell I/σI is better for resolution cutoff selection.