BiochemistryJournal of Biological ChemistryPeer-reviewed
The hyaluronan-binding activity of aggrecan is important, but not essential, for its specific insertion into perineuronal nets
Matthew Y. Otsuka, Leslie Brian Essel, Ashis Sinha…·Samuel Bouyain
This study reports the co-crystal structure of aggrecan's G1 region with and without HA and shows that HA-binding is important but not essential for its integration into perineuronal nets.