Author

Martín Baron

University of ManchesterORCID 0000-0002-7375-5784Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:Drosophila· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Alex Vincent PostmaiD· 1 shared Ana TöpfiD· 1 shared Barbara J.M. MulderiD· 1 shared Bernard D. KeavneyiD· 1 shared Connie R. BezzinaiD· 1 shared David Scott WinlawiD· 1 shared Donna J. PageiD· 1 shared Elisavet FotiouiD· 1 shared

Activity by Year

2018-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperGenetics

Alex Vincent PostmaORCID

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3 papers

Recent·Most cited

Analysis of cancer mutations introduced into the Drosophila Notch Negative Regulatory Region uncovers a diversity of regulatory outcomes

Hideyuki Shimizu, Martín Baron

This study introduces cancer mutations into the Drosophila Notch NRR and identifies diverse regulatory outcomes, including constitutive activation and altered turnover.

bioRxiv · Sep 1, 2025 · PreprintCell Biology

Heterogeneity of NOTCH3 activation mechanisms uncovers therapeutic potential for targeted therapies for CADASIL.

Samira Hosseini-Alghaderi, Martín Baron

This study identifies heterogeneous NOTCH3 activation mechanisms in CADASIL mutants, suggesting therapeutic strategies targeting endocytic pathways rather than direct NOTCH3 signaling.

bioRxiv · Nov 17, 2024 · PreprintCell Biology

Deleterious genetic variants in NOTCH1 are a major contributor to the incidence of non-syndromic Tetralogy of Fallot

Donna J. Page, Matthieu J. Miossec, Simon G. Williams, Elisavet Fotiou, Richard M. Monaghan, Heather Jane Cordell, Louise Sutcliffe, Ana Töpf, Mathieu Bourgey, Guillaume Bourque, Robert J. M. Eveleigh, Sally L. Dunwoodie, David Scott Winlaw, Shoumo Bhattacharya, Jeroen Breckpot, , Bernard D. Keavney

The paper identifies NOTCH1 variants as a major genetic contributor to non-syndromic Tetralogy of Fallot, with 6% of patients carrying deleterious variants.

bioRxiv · Apr 13, 2018 · PreprintGenetics