Author

Samira Hosseini-Alghaderi

University of ManchesterORCID 0000-0003-3743-8789Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Martín BaroniD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

1 paper

Recent·Most cited

Cell BiologybioRxivPreprintNov 17, 2024

Heterogeneity of NOTCH3 activation mechanisms uncovers therapeutic potential for targeted therapies for CADASIL.

Samira Hosseini-Alghaderi, Martín Baron

This study identifies heterogeneous NOTCH3 activation mechanisms in CADASIL mutants, suggesting therapeutic strategies targeting endocytic pathways rather than direct NOTCH3 signaling.

DOI 10.1101/2024.11.17.623993

humanproteomics

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