Author

Jeremy B. Chang

University of California, San FranciscoORCID 0000-0002-7381-6444Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Organism:human· 1 Approach:mechanistic / dynamical model· 1

Frequent Co-Authors

Aaron N. HataiD· 1 shared Anahita Nimbalkar· 1 shared Chendi LiiD· 1 shared Christopher J. GraseriD· 1 shared Lee ZouiD· 1 shared Melissa D Vieira· 1 shared Mohammad U. Syed· 1 shared Radhika KoranneiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Aaron N. HataORCID

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1 paper

Recent·Most cited

Targeted therapy-induced chromosomal instability dictates mitotic dependency on Aurora Kinase A

Chendi Li, Varuna Nangia, Melissa D Vieira, Anahita Nimbalkar, Christopher J. Graser, Jeremy B. Chang, Mohammad U. Syed, Yi Shen, Radhika Koranne, Lee Zou, Xueqian Gong, Sabrina L. Spencer, Aaron N. Hata

This study shows that KRASG12C inhibition induces chromosomal instability (CIN) in NSCLC cells, which synergizes with Aurora Kinase A inhibition to enhance therapeutic efficacy.

bioRxiv · Jan 23, 2026 · PreprintCancer Biology