Author
University of Colorado BoulderORCID 0000-0001-5142-4653Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Chendi Li, Varuna Nangia, Melissa D Vieira…·Aaron N. Hata
This study shows that KRASG12C inhibition induces chromosomal instability (CIN) in NSCLC cells, which synergizes with Aurora Kinase A inhibition to enhance therapeutic efficacy.
Varuna Nangia, Humza M. Ashraf, Nasreen C. Marikar…·Sabrina L. Spencer
The paper identifies Cyclin D1 accumulation as a critical bottleneck for cell-cycle re-entry in drug-treated melanoma cells, driven by MAPK and mTORC1 signaling integration.
Christopher Ryland Ill, Nasreen C. Marikar, Vu Nguyen…·Sabrina L. Spencer
The paper identifies off-target activation of GCN2 by BRAF and EGFR inhibitors, showing it limits cancer cell proliferation.