NeurosciencebioRxivPreprint
Kinase activity simultaneously determines the constitutive and the orthosteric gating in α4β1/3δ GABAA receptors in hippocampal granule cells
Nils Ole Dalby, Ulrike Leurs, Christina Birkedahl Falk‐Petersen…·Petrine Wellendorph
The paper shows that kinase activity affects both constitutive and agonist-induced gating of 4β1/3δ GABAA receptors in hippocampal granule cells, altering ligand efficacy and antagonist effects.
DOI 10.1101/318543