This study investigates MOMP assembly in Corynebacterium glutamicum, showing that PorH and ProtX are inserted at polar growth zones and linked to the cell wall.

Proceedings of the National Academy of Sciences · Oct 1, 2026Peer-reviewedMicrobiology

A TmaT-AftD interaction is required for the CmpL4 mycomembrane biogenesis pathway in Corynebacterium glutamicum.

Anastacia R. Parks, Eric D. Snow, Victoria M. Marando, Michael J. James, Vincent de Bakker, Laura L. Kiessling, Suzanne Walker, Thomas G. Bernhardt

This paper identifies the TmaT-AftD interaction as essential for mycolate transport via the CmpL4 pathway and AG synthesis in Corynebacterium glutamicum.

bioRxiv · Jul 31, 2026 · PreprintMicrobiology

Benchmarking Boltz-2 for Screening of Therapeutic Antibody-Antigen Interactions

Alexandra Fieux-Castagnet, Julian Waton, Alina Glukhonemykh, Eric Snow, Roshini Ashokkumar, Jess Fleming, David Champagne, Thomas Devenyns, Alex Peluffo, Christoforos Anagnostopoulos

The paper benchmarks Boltz-2 for screening therapeutic antibody-antigen interactions, finding weak but above-chance discrimination and limited benefit from extensive sampling.

bioRxiv · May 14, 2026 · PreprintBioinformatics

The mechanism of peptidoglycan O-acetylation in Gram-negative bacteria typifies bacterial MBOAT-SGNH acyltransferases

Alexander C. Anderson, Bailey J. Schultz, Eric D. Snow, Ashley S. Brott, Stefen Stangherlin, Tyler Malloch, J. R. London, Suzanne Walker, Anthony J. Clarke

This study elucidates the mechanism of MBOAT-SGNH acyltransferases in Gram-negative bacteria, showing that a tyrosine-containing peptide shuttles acyl groups from MBOAT to SGNH active sites for peptidoglycan O-acetylation.

Journal of Biological Chemistry · Apr 23, 2025Peer-reviewedBiochemistry