Author

Xiangru Huo

Howard Hughes Medical InstituteORCID 0000-0002-7466-4665Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:ChIP-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Aleksandra A. GalitsynaiD· 1 shared Bo WeniD· 1 shared Denis L. Lafontaine· 1 shared Emily NavarreteiD· 1 shared Hoang TraniD· 1 shared Jack D. HueyiD· 1 shared Jiang Min· 1 shared Job DekkeriD· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperGenomics

Aleksandra A. GalitsynaORCID

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2 papers

Recent·Most cited

Stepwise reorganization of chromosome conformation and nuclear organization during stem cell differentiation

Xiangru Huo, Denis L. Lafontaine, Thomas M. Reimonn, Liyan Yang, Richard Siller, Jack D. Huey, Jiang Min, Aleksandra A. Galitsyna, Vedat Yilma, Krishna Mohan Parsi, Emily Navarrete, Hoang Tran, Leonid A. Mirny, René Maehr, Johan Harmen Gibcus, , Nezar A. Abdennur

The paper temporally maps nuclear reorganization during human stem cell differentiation and identifies three temporally ordered transitions in nuclear structure and function.

bioRxiv · Sep 18, 2026 · PreprintGenomics

G9a/GLP-Sensitivity of H3K9me2 Demarcates Two Types of Genomic Compartments

Zixiang Yan, Luzhang Ji, Xiangru Huo, Qianfeng Wang, Yuwen Zhang, Bo Wen

This study shows that H3K9me2 levels in differentiated cells correlate with genomic compartments and that inhibiting G9a/GLP affects chromatin structure and gene expression.

Genomics Proteomics & Bioinformatics · Aug 1, 2020Peer-reviewedGenomics