Author

Jack D. Huey

University of Massachusetts Chan Medical SchoolORCID 0000-0003-3463-7192Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Genomics· 3 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:gene regulatory network inference· 3 Organism:human· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Assay:ChIP-seq· 2 Research Focus:differential expression· 2 Assay:ATAC-seq· 1

Frequent Co-Authors

Krishna Mohan ParsiiD· 2 shared Nezar A. AbdennuriD· 2 shared René MaehriD· 2 shared Adriano BolondiiD· 1 shared Aleksandra A. GalitsynaiD· 1 shared Alexander MeissneriD· 1 shared Alexandro LandshammeriD· 1 shared Alina Rose· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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2 shared papersGenomics

Krishna Mohan ParsiORCID

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4 papers

Recent·Most cited

GenomicsbioRxivPreprintSep 18, 2026

Stepwise reorganization of chromosome conformation and nuclear organization during stem cell differentiation

Xiangru Huo, Denis L. Lafontaine, Thomas M. Reimonn…·Nezar A. Abdennur

The paper temporally maps nuclear reorganization during human stem cell differentiation and identifies three temporally ordered transitions in nuclear structure and function.

DOI 10.64898/2026.09.16.752023

humanHi-C

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GenomicsBioinformaticsPeer-reviewedMay 29, 2024

Bigtools: a high-performance BigWig and BigBed library in Rust

Jack D. Huey, Nezar A. Abdennur

Bigtools provides a high-performance library for generating and querying BigWig and BigBed files in Rust, with Python bindings and cross-platform support.

8 citations

experimental assaysoftware / tool

𝕏 PostBluesky

GenomicseLifePeer-reviewedJan 16, 2023

Discovery and characterization of LNCSOX17 as an essential regulator in human endoderm formation

Alexandro Landshammer, Adriano Bolondi, Helene Kretzmer…·Alexander Meissner

The paper identifies and characterizes LNCSOX17, a lncRNA essential for human endoderm formation, showing its role in regulating transcriptome and differentiation.

5 citations

humanbulk RNA-seq

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BioinformaticsNucleic Acids ResearchPeer-reviewedOct 15, 2021

Factorbook: an Updated Catalog of Transcription Factor Motifs and Candidate Regulatory Motif Sites

Henry Pratt, Gregory Andrews, Nishigandha N. Phalke…·Zhiping Weng

The paper updates Factorbook, a TF-centric database, by expanding its motif catalog and integrating it with ENCODE data to annotate candidate regulatory sites and provide tools for variant and disease analysis.

48 citations

humanChIP-seq

𝕏 PostBluesky