Viral infection drives cell-intrinsic re-localization of the C. elegans immune-repressive STAT transcription factor STA-1
Lakshmi E. Batachari, Tyler D. Bechtel, Zhouxin Shen, Emily R. Troemel
This study shows that C. elegans STA-1, a STAT-like protein, relocalizes from nuclei to cytoplasm during viral infection, acting cell-intrinsically to repress anti-viral defense.
bioRxiv · Jun 29, 2026 · PreprintImmunology