Author

Lakshmi E. Batachari

University of California San DiegoORCID 0000-0003-0553-1858Unclaimed ORCID profile · follow to get notified of new preprints

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Immunology· 2

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Organism:C. elegans· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Emily R. TroemeliD· 2 shared Alyssa Y. Dai· 1 shared Tyler D. BechteliD· 1 shared Zhouxin SheniD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

4 top collaborators · 4 mutual co-author links

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2 shared papersImmunology

Emily R. TroemelORCID

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2 papers

Recent·Most cited

ImmunologybioRxivPreprintJun 29, 2026

Viral infection drives cell-intrinsic re-localization of the C. elegans immune-repressive STAT transcription factor STA-1

Lakshmi E. Batachari, Tyler D. Bechtel, Zhouxin Shen, Emily R. Troemel

This study shows that C. elegans STA-1, a STAT-like protein, relocalizes from nuclei to cytoplasm during viral infection, acting cell-intrinsically to repress anti-viral defense.

DOI 10.64898/2026.06.24.734234

C. elegansbulk RNA-seq

𝕏 PostBluesky

ImmunologyProceedings of the National Academy of SciencesPeer-reviewedJul 9, 2024

C. elegans RIG-I-like receptor DRH-1 signals via CARDs to activate anti-viral immunity in intestinal cells

Lakshmi E. Batachari, Alyssa Y. Dai, Emily R. Troemel

This study identifies DRH-1 as a C. elegans RIG-I-like receptor that uses 2CARD domains to activate anti-viral immunity in intestinal cells, showing parallels with mammalian RIG-I signaling.

25 citations

C. elegansexperimental assay

𝕏 PostBluesky