Author

Marlen Knobloch

University of LausanneORCID 0000-0002-7490-0285Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:cell type annotation· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Assay:metabolomics· 2 Approach:statistical model· 2 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Diana PanfilovaiD· 2 shared Francesco PetrelliiD· 2 shared Alicia ReyiD· 1 shared Andreas SagneriD· 1 shared Charline Carron· 1 shared Frédéric CasséiD· 1 shared Hadrien Soldati· 1 shared Héctor Gallart‐AyalaiD· 1 shared

Activity by Year

2024-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersCell Biology

Diana PanfilovaORCID

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4 papers

Recent·Most cited

Endogenous lipid droplets exhibit profound proteomic and lipidomic differences across neural stem cell states

Diana Panfilova, Mergim Ramosaj, Manfredo Quadroni, Marlen Knobloch

The paper identifies state-dependent proteomic and lipidomic differences in lipid droplets of neural stem/progenitor cells and shows CIDEB's role in maintaining quiescence.

bioRxiv · Aug 20, 2026 · PreprintCell Biology

An optimized method to visualize lipid droplets in brain tissue demonstrates their substantial accumulation in aged brains

Alicia Rey, Francesco Petrelli, Diana Panfilova, Sofia Madsen, Noéline Héritier, Marlen Knobloch

Cell Reports Methods · May 14, 2026Peer-reviewedNeuroscience

Distinct epigenetic and metabolic states reflect the regional identity of adult neural stem cells and prime their fate

Valentina Scandella, Nikolaos M. R. Lykoskoufis, Hadrien Soldati, Livia Di Martino, Tony Teav, Héctor Gallart‐Ayala, Julijana Ivanišević, Simon M. G. Braun, Marlen Knobloch

This study identifies niche-specific chromatin and metabolic states in adult mouse neural stem cells that influence their neuronal fate potential.

bioRxiv · Jan 26, 2026 · PreprintCell Biology

Astrocyte-derived PEA116 increases adult hippocampal neurogenesis and confers stress resilience

Charline Carron, Frédéric Cassé, Sébastien Sultan, Thomas Larrieu, Kevin Richetin, Jeanne Espourteille, Nicolas Robadey, Marta Vilademunt, Andreas Sagner, Francesco Petrelli, Marlen Knobloch, Ruth Beckervordersandforth, Nicolas Toni

This study identifies PEA116, an astrocyte-derived peptide that enhances adult hippocampal neurogenesis and stress resilience by promoting aNSC proliferation through ERK2 phosphorylation.

bioRxiv · Sep 27, 2024 · PreprintNeuroscience