Ulrich Tepaß

The paper investigates whether tissue-level mechanics during Drosophila germ-band extension influence neuroblast ingression dynamics and finds that cell-intrinsic mechanisms maintain ingression kinetics despite changes in tissue fluidity.

This study uses optogenetics to enhance E-cadherin clustering in Drosophila embryos, revealing its role in regulating cell intercalation and convergent extension during morphogenesis.

This study shows that mitotic polarity oscillation drives epithelial tumor progression by linking cell division and loss of polarity through a feedforward mechanism.

This study identifies the role of the Crumbs complex in regulating apical membrane dynamics during epithelial cell ingression, showing its necessity for proper timing and execution of the process.