Author

Claudia C.S. Chini

Mayo ClinicORCID 0000-0002-7499-8921Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:mouse· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Aaron Warren· 1 shared Adriana Marques-Carvalho· 1 shared Ana Resende-CoelhoiD· 1 shared Ankita Chalke· 1 shared Benjamin Stronach· 1 shared Chan‐Il Choi· 1 shared Claudia Francesca LucchinettiiD· 1 shared Eduardo N Chini· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperMolecular Biology

Aaron Warren

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintJul 11, 2025

Estrogens protect bone mass by inhibiting NAD+ metabolism in osteoclasts

Adriana Marques-Carvalho, Gareeballah Osman Adam, Ankita Chalke…·Maria Almeida

This study shows estrogens protect bone mass by inhibiting NAD+ metabolism in osteoclasts, reducing bone resorption through suppression of SIRT3 activity.

DOI 10.1101/2025.07.11.664289

mousehuman

𝕏 PostBluesky

NeuroscienceJournal of NeurosciencePeer-reviewedSep 7, 2021

Critical role for astrocyte NAD+ glycohydrolase in myelin injury and regeneration

Monica Renee Langley, Chan‐Il Choi, Thais Peclat…·Isobel A. Scarisbrick

This study shows that CD38 in astrocytes mediates NAD+ depletion and myelin damage caused by high fat diets and demyelination, with CD38 inhibitors improving myelin regeneration.

30 citations

mousebulk RNA-seq

𝕏 PostBluesky