Author

Claudia Francesca Lucchinetti

Mayo ClinicORCID 0000-0001-5070-1196Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Assay:proteomics· 1

Frequent Co-Authors

Yong GuoiD· 2 shared Caiyun Liu· 1 shared Chan‐Il Choi· 1 shared Claudia C.S. ChiniiD· 1 shared Eduardo N. ChiniiD· 1 shared Fangfang QiiD· 1 shared Husheng Ding· 1 shared Hyesook Yoon· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersNeuroscience

Yong GuoORCID

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2 papers

Recent·Most cited

NeuroscienceJournal of Clinical InvestigationPeer-reviewedFeb 10, 2026

Neutrophil-microglia interaction drives reversible motor dysfunction in neuromyelitis optica model induced by subarachnoid AQP4-IgG

Fangfang Qi, Vanda A. Lennon, Shunyi Zhao…·Long-jun Wu

The paper shows that neutrophil-derived C5a signaling through microglial C5aR1 drives reversible motor dysfunction in a mouse NMO model induced by AQP4-IgG.

3 citationstop 2%

mouseexperimental assay

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NeuroscienceJournal of NeurosciencePeer-reviewedSep 7, 2021

Critical role for astrocyte NAD+ glycohydrolase in myelin injury and regeneration

Monica Renee Langley, Chan‐Il Choi, Thais Peclat…·Isobel A. Scarisbrick

This study shows that CD38 in astrocytes mediates NAD+ depletion and myelin damage caused by high fat diets and demyelination, with CD38 inhibitors improving myelin regeneration.

30 citations

mousebulk RNA-seq

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