PathologyAdvanced SciencePeer-reviewed
D-glucuronyl C5-epimerase binds to EGFR to suppress kidney fibrosis
Xiaoqi Jing, Jun Wu, Jingru Ning…·Kan Ding
This study identifies Glce as a key regulator of kidney fibrosis by binding to EGFR and inhibiting EMT through the TGF-β/Smad pathway, independent of its enzymatic activity.
5 citations