Cancer BiologybioRxivPreprint
In vivo isogenic modelling unveils TP53-associated relapse trajectories in T-cell acute lymphoblastic leukemia
Stéphanie Gachet, Samuel Quentin, Lucie Hernandez…·Jean Soulier
This study uses patient-derived xenografts to identify TP53-associated relapse mechanisms in T-ALL, showing relapse phenotypes linked to OXPHOS metabolism and MYC signaling.
DOI 10.64898/2026.01.19.700255