GenomicsGenome biologyPeer-reviewed
Robust identification of extrachromosomal DNA and genetic variants using multiple genetic abnormality sequencing (MGA-Seq)
Da Lin, Yanyan Zou, Xinyu Li…·Gang Cao
This study introduces MGA-Seq, a method to detect multiple genomic abnormalities, and finds that focal amplification in tumors is heterogeneous and reveals ecDNA network architecture.