Da Lin

This study introduces MGA-Seq, a method to detect multiple genomic abnormalities, and finds that focal amplification in tumors is heterogeneous and reveals ecDNA network architecture.

The paper develops MiP-Seq, a multiomics in situ sequencing method, to analyze spatial gene profiles, mutations, and RNA modifications at single-cell resolution.

CoolBox is a flexible open-source toolkit for visualizing genomics data, compatible with Python, offering customization and integration with Jupyter and web browsers.

The paper introduces DLO Hi-C Tool for analyzing DLO Hi-C data, providing a pipeline from raw reads to contact maps with quality controls and efficient processing.

CoolBox provides an interactive genomic data exploration tool for Jupyter Notebook with a ggplot2-like API and GUI support for multi-omics data.