Bing Yang

Visible-Light-Controlled Residue-Selective Cross-Linking for Deciphering Protein Complexes and Dynamic Protein-Protein Interactions in Live Cells

This paper introduces a visible-light-controlled cross-linking method for analyzing protein complexes and dynamic interactions in live cells, showing improved accuracy and temporal control.

The catalytic activity of microRNA Argonautes plays a modest role in microRNA star strand destabilization in C. elegans

This study shows that miRNA Argonaute slicing has a minor role in star strand destabilization in C. elegans, with limited developmental impact and context-dependent effects.

Robust identification of extrachromosomal DNA and genetic variants using multiple genetic abnormality sequencing (MGA-Seq)

This study introduces MGA-Seq, a method to detect multiple genomic abnormalities, and finds that focal amplification in tumors is heterogeneous and reveals ecDNA network architecture.

The developmentally-timed decay of an essential microRNA family is seed sequence-dependent

The paper shows that the decay of the mir-35 miRNA family in C. elegans is seed sequence-dependent and selectively regulates all members of the family during development.

Regulated nuclear accumulation of a histone methyltransferase times the onset of heterochromatin formation in C. elegans embryos

The paper shows that MET-2/SETDB1 and its interactors LIN-65/ATF7IP and ARLE-14/ARL14EP regulate the timing of heterochromatin formation during C. elegans embryogenesis.