Author

Pablo Alfredo Ortiz

Henry Ford HealthORCID 0000-0002-7512-7255Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:metabolism & bioenergetics· 1 Organism:rat· 1

Frequent Co-Authors

Ankita Bachhawat JaykumariD· 1 shared César A. RomeroiD· 1 shared Hong WangiD· 1 shared Mariela MéndeziD· 1 shared Nour‐Eddine Rhaleb· 1 shared Sumit R. MonuiD· 1 shared Xiaoping YangiD· 1 shared Xu Jiang· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 16 mutual co-author links

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1 shared paperPhysiology

Ankita Bachhawat JaykumarORCID

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2 papers

Recent·Most cited

ALMS1 KO rat: a new model of metabolic syndrome with spontaneous hypertension

Ankita Bachhawat Jaykumar, Sumit R. Monu, Xu Jiang, Mariela Méndez, Xiaoping Yang, Nour‐Eddine Rhaleb, Pablo Alfredo Ortiz

This study characterizes an ALMS1 knockout rat model, showing it develops metabolic syndrome with hypertension, obesity, and hyperleptinemia, revealing ALMS1's role in metabolic regulation and its sex- and age-dependent effects.

Acta Physiologica · Feb 15, 2026Peer-reviewedPhysiology

Luminal Flow in the Connecting Tubule induces Afferent Arteriole Vasodilation

Hong Wang, Pablo Alfredo Ortiz, César A. Romero

The paper investigates how luminal flow in the connecting tubule induces afferent arteriole vasodilation through ENaC activation and O2- production, independent of nitric oxide synthase.

Clinical and Experimental Nephrology · Jan 12, 2025Peer-reviewedPhysiology