Author

Amani Hassan

McGill UniversityORCID 0000-0002-7542-6976Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Approach:statistical model· 1

Frequent Co-Authors

Anie PhilipiD· 2 shared Kenneth W. FinnsoniD· 2 shared Tenzin KungyaliD· 2 shared Varsha Reddy Durgempudi· 2 shared Dieter Peter ReinhardtiD· 1 shared Nader SadeghiiD· 1 shared Valentin NeleaiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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2 shared papersCancer Biology

Anie PhilipORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintSep 3, 2026

A CD109-SMURF2 Axis Diverts EGFR from Degradation to Sustain Oncogenic Signaling and Promote Squamous Cell Carcinoma Invasion and Stemness

Tenzin Kungyal, Amani Hassan, Kenneth W. Finnson…·Anie Philip

This study identifies the CD109-SMURF2 axis as a mechanism that prevents EGFR degradation, sustaining oncogenic signaling and promoting SCC invasion and stemness.

DOI 10.64898/2026.09.02.748398

humanbulk RNA-seq

𝕏 PostBluesky

Cancer BiologybioRxivPreprintJun 23, 2026

Rewiring of EGFR oncogenic program by opposing actions of membrane versus soluble CD109 in HNSCC

Varsha Reddy Durgempudi, Tenzin Kungyal, Amani Hassan…·Anie Philip

This study shows that soluble CD109 inhibits EGFR signaling and cancer stemness in HNSCC by blocking mCD109-EGFR interactions and promoting EGFR degradation.

DOI 10.64898/2026.06.20.733552

humanproteomics

𝕏 PostBluesky