Author
InsermORCID 0000-0002-6704-2032Unclaimed ORCID profile · follow to get notified of new preprints
4 papers
Recent·Most cited
Margaux Oberling, Mathieu Landry, Yann Aubert…·Margherita Ghisi
This study identifies PTBP1-CDC42 splicing regulation as a critical factor in AML growth and venetoclax sensitivity, suggesting a therapeutic combination strategy.
Binje Vick, Vindi Jurinović, Kristina Kuhbandner…·Irmela Jeremias
The paper develops patient-derived AML PDX models that replicate primary AML biology and include subgroups lacking existing models, showing reduced leukemia growth after long-term chemotherapy.
Sarah J. Skuli, A’ishah Bakayoko, Marisa Kruidenier…·Martin P Carroll
This study identifies GGPP, a mevalonate pathway byproduct, as critical for chemoresistance in TP53mut AML through ROS regulation and mitochondria stress response, suggesting statin-based therapies could be effective.