Author

Cheng Yong Tham

National University of SingaporeORCID 0000-0002-7594-3025Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Bioinformatics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Daniel Geoffrey TeneniD· 2 shared Roberto Tirado-MagallanesiD· 2 shared Touati BenoukrafiD· 2 shared Wee Joo ChngiD· 2 shared Alexander H. van Asbeck· 1 shared Alexandre H. ThiéryiD· 1 shared Anand Devaprasath D. JeyasekharaniD· 1 shared Bryan T. H. KohiD· 1 shared

Activity by Year

2020-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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2 shared papersMolecular Biology

Daniel Geoffrey TenenORCID

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3 papers

Recent·Most cited

BioengineeringbioRxivPreprintMar 10, 2026

A Universal, AI-based Design Framework for Efficient Manufacturing of mRNA Therapeutics

Kuo‐Chieh Liao, Giuseppe Maccari, Giorgio Ciano…·Duccio Medini

This paper introduces an AI framework to improve mRNA therapeutic manufacturing by predicting and optimizing sequence design for in vitro transcription efficiency.

DOI 10.64898/2026.03.09.710039

deep learningdrug response / drug discovery

𝕏 PostBluesky

Molecular BiologybioRxivPreprintJun 10, 2020

TIP60 acetylates H2AZ and regulates doxorubicin-induced DNA damage sensitivity through RAD51 transcription

Kwok Kin Lee, Yanzhou Zhang, Roberto Tirado-Magallanes…·Sudhakar Jha

This study shows TIP60 acetylates H2AZ, affecting DNA repair gene expression and doxorubicin sensitivity through RAD51 transcription.

3 citations

humanChIP-seq

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BioinformaticsGenome biologyPeer-reviewedMar 3, 2020

NanoVar: Accurate Characterization of Patients’ Genomic Structural Variants Using Low-Depth Nanopore Sequencing

Cheng Yong Tham, Roberto Tirado-Magallanes, Yufen Goh…·Touati Benoukraf

NanoVar accurately detects structural variants using low-depth Nanopore sequencing, achieving high F1 score in simulated data and uncovering normal alleles in patient samples.

129 citationstop 1%

humanwhole-genome sequencing

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