Touati Benoukraf

ColocZStats: A Z-Stack Signal Colocalization Extension Tool for 3D Slicer

ColocZStats is a 3D Slicer extension that enables colocalization analysis on z-stacks with user-defined ROIs and thresholding.

Representing Transcription Factor Dimer Binding Sites Using Forked-Position Weight Matrices and Forked-Sequence Logos

The paper introduces forkedTF, a tool to create FPWM and F-Logos for modeling TF dimer binding sites, and provides precomputed resources in MethMotif 2024.

Formation and recycling of an active epigenetic mark mediated by cell cycle-specific RNAs

The paper shows that cell cycle-specific long noncoding RNAs regulate the establishment and recycling of the acetylated histone H2A.Z epigenetic mark.

Targeted intragenic demethylation initiates chromatin rewiring for gene activation

CRISPR-DiR induces locus-specific demethylation and chromatin remodeling to reactivate the p16 gene.

TIP60 acetylates H2AZ and regulates doxorubicin-induced DNA damage sensitivity through RAD51 transcription

This study shows TIP60 acetylates H2AZ, affecting DNA repair gene expression and doxorubicin sensitivity through RAD51 transcription.

NanoVar: Accurate Characterization of Patients’ Genomic Structural Variants Using Low-Depth Nanopore Sequencing

NanoVar accurately detects structural variants using low-depth Nanopore sequencing, achieving high F1 score in simulated data and uncovering normal alleles in patient samples.

ZBTB33 (Kaiso) methylated binding sites are associated with primed heterochromatin

The paper investigates ZBTB33's role as a methylated DNA binding factor, revealing its association with primed heterochromatin through chromatin state analysis.