Author

Yanzhou Zhang

Beth Israel Deaconess Medical CenterORCID 0000-0001-5866-7578Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Genetics· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1

Frequent Co-Authors

Alexander K. Ebralidze· 2 shared Annalisa Di RuscioiD· 2 shared Bon Q. TrinhiD· 2 shared Daniel Geoffrey TeneniD· 2 shared Mahmoud Adel BassaliD· 2 shared Roberto Tirado-MagallanesiD· 2 shared Simone UmmarinoiD· 2 shared Touati BenoukrafiD· 2 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersMolecular Biology

Alexander K. Ebralidze

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3 papers

Recent·Most cited

Molecular BiologyCellsPeer-reviewedNov 2, 2021

NAD modulates DNA methylation and cell differentiation

Simone Ummarino, Clinton Hausman, Giulia Gaggi…·Annalisa Di Ruscio

This study shows that NAD affects DNA methylation and cell differentiation by promoting ADP-ribosylation of DNMT1, leading to CEBPA activation and myeloid differentiation.

28 citations

humanDNA methylation

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GeneticsbioRxivPreprintOct 27, 2021

Formation and recycling of an active epigenetic mark mediated by cell cycle-specific RNAs

Alexander K. Ebralidze, Simone Ummarino, Mahmoud Adel Bassal…·Daniel Geoffrey Tenen

The paper shows that cell cycle-specific long noncoding RNAs regulate the establishment and recycling of the acetylated histone H2A.Z epigenetic mark.

2 citations

long-read sequencingexperimental assay

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Molecular BiologybioRxivPreprintJun 10, 2020

TIP60 acetylates H2AZ and regulates doxorubicin-induced DNA damage sensitivity through RAD51 transcription

Kwok Kin Lee, Yanzhou Zhang, Roberto Tirado-Magallanes…·Sudhakar Jha

This study shows TIP60 acetylates H2AZ, affecting DNA repair gene expression and doxorubicin sensitivity through RAD51 transcription.

3 citations

humanChIP-seq

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