Sujoy Ghosh

This study identifies a metabolic myopathy in HFpEF through multiomics analysis of skeletal muscle, revealing mitochondrial dysfunction and altered amino acid metabolism.

The paper identifies Esrra as a master regulator of adaptive hepatic translation during prolonged starvation by inducing Rplp1 expression and lysosome/autophagy protein translation.

The paper constructs gene regulatory networks in visceral adipose tissue from obese and non-obese individuals, identifies altered network connectivity patterns, and validates novel gene candidates influencing adipocyte differentiation.

This study develops an optimized siRNA transfection protocol for human and mouse adipocyte cultures throughout differentiation, improving gene knockdown efficiency.

This study identifies Esrra's role in regulating Rplp1-mediated translation of lysosomal and autophagy proteins during NASH, showing that alternate day fasting can reverse these effects.