Author

Patricia A. Fitzgerald-Bocarsly

Rutgers New Jersey Medical SchoolORCID 0000-0002-7604-3184Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cell Biology· 1 Genomics· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Assay:scRNA-seq· 2 Approach:statistical model· 2

Frequent Co-Authors

Elizabeth Akbulut· 3 shared Paolo S. TuranoiD· 3 shared Ricardo Iván Martínez‐ZamudioiD· 3 shared Utz HerbigiD· 3 shared Themistoklis VasilopoulosiD· 2 shared George S. YapiD· 1 shared Hannah K. DewaldiD· 1 shared Luis Garza-MartíneziD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersSystems Biology

Elizabeth Akbulut

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3 papers

Recent·Most cited

A transitional senescence program drives inflammatory monocyte state expansion in aging humans

Themistoklis Vasilopoulos, Paolo S. Turano, Luis Garza‐Martinez, Elizabeth Akbulut, Mounika Konda, Utz Herbig, Patricia A. Fitzgerald-Bocarsly, Ricardo Iván Martínez‐Zamudio

The paper identifies a senescence-like transitional state in aging human monocytes driven by AP-1, leading to inflammatory monocyte expansion and systemic inflammation.

bioRxiv · Sep 13, 2026 · PreprintSystems Biology

Epigenetic mechanisms regulating CD8+ T cell senescence in aging humans

Paolo S. Turano, Elizabeth Akbulut, Hannah K. Dewald, Themistoklis Vasilopoulos, Patricia A. Fitzgerald-Bocarsly, Utz Herbig, Ricardo Iván Martínez‐Zamudio

This study identifies epigenetic regulators of CD8+ T cell senescence in aging humans using multiomic profiling and shows their relevance to disease progression.

Cell Reports · Dec 31, 2025Peer-reviewedGenomics

Senescent CD8+ T Effector Memory Cells are Functionally Impaired, Enriched in Aging and Disease, and a Barrier to Immunotherapy

Paolo S. Turano, Elizabeth Akbulut, Nica Mariz Aquino, Luis Garza-Martínez, Sukhwinder Singh, George S. Yap, Patricia Fitzgerald-Bocarsly, Ricardo Iván Martínez-Zamudio, Utz Herbig

This study identifies senescent CD8+ T effector memory cells as functionally impaired and enriched in aging and disease, and shows they hinder immunotherapy responses.

bioRxiv · Dec 19, 2025 · PreprintCell Biology